Alcohol use is three times greater among Indian youth than among adolescents in general. Research suggests that an adolescent's decisions concerning substance abuse may be tied to self-esteem and to peer associations and activities. This booklet examines three types of programs that have been successful in building positive self-concepts and peer support groups among Native American youth. The Eastern Band of Cherokee (North Carolina) sponsors the Cherokee Challenge program. This program involves 45 adolescents and their families in weekly meetings and monthly outdoor challenge activities that foster self-confidence, problem-solving skills, and group communication and trust. Working with an outreach worker, the Pascua Yaqui tribe in southern Arizona has adapted the national Girl Scout program to its community needs. The national organization provided assistance in getting the local program organized, training for volunteer leadership, program materials, access to camping facilities, and recognition for scouts and leaders through established awards and achievement programs. Window Rock Public High School on the Navajo Reservation (Arizona) has a peer support program for youth struggling with problems of their own or someone else's substance abuse. Groups of about seven students and two trained adult facilitators meet weekly to help students explore their self-identity and cultural identity, build self-worth, and reinforce good choices. Contact information is provided for each program. (SV)