The Mathematics 16 program provides for the development of essential concepts, skills, and attitudes required for effective computation and problem solving. The program is activity-based, and addresses the need for students to be able to transfer and apply specific mathematical concepts and skills to more generalized situations in everyday life and the world of work. A focus on the use of technology throughout the program assists students to develop the ability to use calculators and computers in performing routine tasks more easily replicated by these technologies. This guide contains the program of studies and curriculum guide for the Science 16 program. Contents include chapters which are entitled: (1) "Rationale"; (2) "Philosophy"; (3) "Goals for the Mathematics 16 Program"; (4) "Model for the Mathematics 16 Program"; (5) "Interpersonal Skills and the Social Sphere"; (6) "Required and Elective Components"; (7) "Planning"; (8) "Learning Resources for Mathematics 16"; (9) "Methodology"; (10) "Evaluation"; (11) "Scope and Sequence"; (12) "Program of Studies/Presentation of Content"; and (13) "Suggested Options." (KR)