The Science 16 program provides for the development of essential concepts, skills, and attitudes in science that will enable students to function successfully in the home, classroom, workplace, and community. The program is activity-based, and provides opportunities for students to relate essential concepts, skills, and attitudes to their own world of experience and needs. Societal issues involving science and technology have been integrated throughout the program. Community partnerships provide opportunities for students to become involved in the community by way of meaningful activity linked to the science program. Strategies and skills for scientific inquiry, problem solving, and decision making included throughout the Science 16 program provide students with a systematic and logical approach for dealing with a variety of phenomena encountered in their environment. This manual has been developed to assist classroom teachers to implement the Integrated Occupational Science 16 program. This manual should be used as a practical planning and instructional tool in translating the intentions of the Science 16 program. Contents include: (1) further information about the goals and objectives of the science program; (2) thematic contexts for the delivery of prescribed concepts, skills, and attitudes; (3) suggestions for planning and implementing the program; (4) suggestions for relating science instruction to essential life skills; (5) suggestions for using community resources to provide instruction in science; (6) situational and concrete approaches for developing an understanding of the interactions among science, technology, and society; (7) suggestions for developing thinking and communicating skills; and (8) suggestions for assessing and evaluating student progress. (KR)