In recent years state governments have taken steps to strengthen their economic bases by promoting growth of high-technology industries within their borders. A byproduct of this effort has been an increasing need for information on the geographic distribution of research and development (R&D) expenditures. The information in this report permits detailed analysis of state- and region-specific R&D activities by industry, academia, nonprofit institutions, and federal agencies. The first section contains highlights and summary information on state and regional R&D concentration levels. Comparisons between the distribution of R&D performance and other socioeconomic variables are included. The second section deals more specifically with R&D performance patterns within each of the nine geographic regions. Appendix A details data sources used in the creation of this report. Data are presented in tabular form for state, region, and performance sector in appendix B. Appendix C consists of personnel and funding profiles for each of the 50 states, the District of Columbia, and the total United States. (CW)