This report focuses on three 11-day summer institutes on "The Impact of Toxic and Hazardous Materials on Humans and the Environment" conducted for 90 secondary school science teachers over the course of three summers at Sonoma State University, California. These summer institutes were all followed up with in-service days during the following academic year. The third year of the program targeted mentor teachers or teachers who would conduct an in-service program for their district. The theme of hazardous materials proved to be an excellent way of integrating basic science principles, recent advances in science, science and engineering technologies, and the relationship and role of science in society. Twenty-five curriculum modules/laboratory exercises were developed, field tested, and critiqued by peers. Field trips were taken to 11 sites to illustrate specific concepts or problems covered in the program. The gap between the private industrial sector and the educational sector was bridged with these numerous site visits and opportunities for interaction with experts from industry. A summary evaluation shows that all of the participants have introduced topics covered in the institute into their teaching, and 81% of their students are considering careers related to subjects covered in the institute. An institute brochure is appended. (Author/SM)