This conference report focuses upon transition issues for those individuals with profound multiple-sensory impairments. It contains presentations, reactions, and syntheses of discussions by working groups. The keynote address, by H. D. Bud Fredericks, is titled "Those with Profound Handicaps: Who Are They? How Can They Be Served?." Section I begins with a paper by Lyle Romer titled "Community-based Residential Options for Persons with Severe/Multiple Disabilities: Impact of Services on People's Lifestyles," followed by responses by George Singer and Stephen Barrett. Section II opens with a paper by Paul Wehman and Janet Hill, titled "Supported Competitive Employment for Persons Labeled Severely and Profoundly Mentally Retarded: Impact of Wages and Integration," with responses by Kevin Lessard and Nancy Norman. A section on the health and psychosocial aspects of transition contains a paper by Sharon Hostler called "Youth with Profound Multiple Handicaps of Deaf-Blindness: Health Issues in Their Transition," accompanied by responses by Mary O'Donnell and Hank Bersani, Jr. The final section includes "Recreation and Leisure: Practices in Educational Programs Which Hold Promise for Adult Service Models" by Lori Goetz, along with a response by Pamela Mathy-Laikko and Terrence Dolan and a second response by Barbara Ryan. (JDD)