The objectives and activities of a 3-year preventive intervention program are described. The project's goal was to demonstrate a comprehensive, coordinated interagency model of preventive intervention for birth to 3-year-old handicapped or at-risk infants and young children. Following an in-hospital screening process of infants delivered at Mid-Maine Medical Center, home visits were made to confirm or negate any suspected risks or handicaps. Identified infants and their families residing in the four-town project area were then referred to the project's interdisciplinary Service Assessment Team for development of a case plan and delivery of services. The report focuses on difficulties in the design and conduct of the project in relation to such issues as interagency collaboration and communication, parental acceptance of project services, hospital screening, prenatal assessment, home visits, and the Service Assessment Team referral process. Among conclusions reached were that any philosophical issues involved in determining which discipline(s) should be involved in the home visit component of the assessment process should be resolved, and that the participating hospital must have full involvement in planning and must endorse the project fully, prior to its beginning. (JW)