This document presents a manual to help program developers plan for a comprehensive school and community-based response to the drug problem as required by the Drug-Free Schools and Communities Act. Part I explains the purpose of the manual and discusses other work being conducted by the North Carolina Alcohol and Drug Defense Program. Part II examines the basis for a sound community effort, explaining the purpose and establishment of a local advisory council and discussing school policies. Part III presents model school-based prevention program components. Four program components are listed, an alcohol and other drug education curriculum is presented, and basic performance standards for alcohol and drug education are stated for kindergarten through grade 3, grades 4 through 6, grades 6 through 8, and grades 9 through 12. Part IV, Model School-Based Intervention Program Components, discusses the case for school-based early intervention programs, the early identification process, assessment, referral, the development of in-school referral resouces, coordination with community resources, and follow-up and aftercare services. Brief summaries are provided of these types of school-based intervention programs to serve youth: (1) student assistant programs; (2) natural helper/peer helper programs; (3) alternate to expulsion programs; and (4) alternate schools. (NB)