Acquired Immune Deficiency Syndrome (AIDS) has become one of the most serious epidemic disease problems in recent years. In 1985 the Public Health Service recommended establishment of test sites where individuals might be tested for Human T Lymphotropic Virus III (HTLV-III) antibody. An HTLV-III antibody screening program was integrated into a community-based health service agency which focused on reproductive health care. The HTLV-III antibody screening program provided a needed testing and counseling service to community residents. Both staff members and community residents benefited by having pertinent and accurate information on AIDS available and accessible. The literature indicates that providing HTLV-III screening and counseling for women of reproductive age prior to their becoming pregnant is the most effective way to prevent perinatal transmission of the virus. Family planning programs with females at risk have a responsibility of providing information and making available testing for the HTLV-III antibody to provide women information regarding the risk. Sensitivity to staff, clients, and community concerns is imperative in implementing an HTLV-III screening program. Careful consideration needs to be given to site, scheduling, voluntary participation, anonymity, and confidentiality as well as clinical services in order to have a successful program. Appendices include information sheets on the blood testing program and procedures. (NB)