This guide presents established principles of learning and instruction, along with practical examples of how these principles can be incorporated into instructional materials. This guidebook is a collection of 55 of the more commonly known principles of learning. The principle statements are first arranged by category of learning. Each category contains several principles with citations of the author of the research and the date the research was published. An interpretation of the meaning of the statement immediately follows the principle. The application describes a specific and concrete use of the principle to the curriculum development process. In some instances graphics are provided to show how the principle would be applied in an actual lesson. The 17 categories are prelearning preparation, individual differences, instructional conditions, motivation, active participation, successful achievement, knowledge of results, practice, rate of presentation, vocabulary/technical terminology, diagnosis, remediation, learning concepts, presentation/format, memory/forgetting, questions, and review/summary. (YLB)