This document is designed for use as a resource and reference guide for Air Force instructional managers who are considering the adoption or expansion of computer-assisted instruction (CAI) at some future time, and also as a decision aid for an instructional manager currently involved in the CAI decision process. The contents are intended to be helpful where CAI systems are already available to the trainers, as well as in those cases in which the adoption of CAI requires new system acquisition. The handbook is divided into five sections: (1) Introduction and History of CAI; (2) Understanding CAI; (3) Critical Factors for Adopting CAI; (4) Decision Aids for Considering the Adoption of CAI; and (5) Resources. The section on decision aids includes worksheets for use in evaluating the need for CAI, identifying configurations most closely matched to instructional needs and practices, and estimating the feasibility of initiating CAI implementation. Resources listed include a glossary, an extensive bibliography, and lists of related associations and periodicals. (THC)