The final report summarizes accomplishments of Project AEROBIC (Aerobic Exercise and Research Opportunities to Benefit Impaired Children), which provided a physical education exercise program for severely, profoundly, and multiply handicapped children aged 10-21. Activities are outlined for the 3 year period and include modification of exercise testing equipment, training of personnel, revision of curricular materials, and adaptation of instructional strategies. Formal, daily physical education progams were established to improve cardiovascular function based on assessment of movement limitation. It was concluded that the population does exhibit increased cardiovascular functioning following participation in a regularly scheduled program of motor activities. The bulk of the report consists of appendixes which include copies of the following papers by Richard Mulholland, Jr. and Alexander W. McNeill: "Cardiovascular Responses of Three Profoundly Retarded, Multiply-Handicapped Children during Selected Motor Activities"; "Consolidation Memory Theory Applied to Relearning Motor Skills in Severely/Profoundly Handicapped Children"; "The Effects of Systematic Ambulation Training on the Cardiovascular Responses of Severely/Profoundly Handicapped Children"; and "Heart Rate Responses of Profoundly Handicapped Children during Closed-Skill Fine Motor and Open-Skill Gross Motor Activities." (CL)