Following a prefatory description of infant development and high-quality infant day care centers, this paper focuses on the construction of learning centers for infants and toddlers in day care. Issues for consideration are specified, and 18 different care/learning centers and 6 work sstations for parents/staff are briefly described. In addition to areas devoted to physical care, learning centers may focus on the following: listening, seeing, hearing, touching, fine motor skills, gross motor skills, and creativity, as well as activities dealing with: sociodrama, water and sand, fantasy, nature, quiet, construction, and adventure. Adult areas are oriented toward observation, parent involvement, office records management, planning, food preparation, and maintenance. Tables indicate relationships of each center station to individual and/or program development and specify possible locations of centers and expected users. (RH)