Based on a program provided by a consortium of mental health centers in the Detroit, Michigan, area, this manual is intended to assist in the development and delivery of programs that allay or prevent the devastating human impact of plant shutdowns and large-scale layoffs. The guide focuses on delivery of programs that promote more effective use of existing community resources, the development of practical strategies for coping with emotional and economic stress, and reemployment by facilitating referral and development of job-finding skills. The manual is organized in five sections. Following an introduction and overview in section I, section II describes the theoretical background immediately relevant to program design. It examines the physical and emotional consequences of job displacement, the life-cycle of related stress, and the particular vulnerability of various sub-populations. Section III explores the issues involved in assessing the total environment prior to program implementation. In section IV, planning considerations for pre-layoff interventions are discussed, while section V presents descriptions of specific program components for immediate adaptation or application. Each component descriptor incorporates summaries of program objectives, strategies for adaptation, prescriptions for avoidance of possible pitfalls, and examples of related materials or guides. Appendixes to the guide include relevant readings, sample formats or guidelines, and resource materials. (KC)