A model drawn from recently expanding research literature is presented to clarify the process involved in the development of clinical depression. A body of literature is reviewed that deals with information processing, specifically memory, which relates to the selective recall of negative experiences clinically seen in depressives. A second body of research dealing with the role of self-awareness is also reviewed. The impact of self-awareness on the amplification of the negative effects of low self-esteem is considered. Conclusions are offered, including that the negative effects of self-awareness occur only with a negative expectancy. The importance of schemes is also discussed. (JAC)