The User's Guide to the Regional Study of Higher Education in Agriculture and Home Economics in the South explains the purpose and organization of the study, one of three phases of a larger investigation being conducted by collaborating researchers in several Agricultural Experiment Stations. The guide provides a detailed description of the methodological procedures and data files employed in the study, which involved determining what aspects of social origins, high school and work experience, and college entry influenced the choice of and attitudes toward an agriculturally related major for over 40,000 Agriculture and Home Economics students at 38 land grant colleges (both 1862 and 1890) and other universities. The discussion of methodology includes the development of instruments, sample design, data collection, response rates, data file specifications and usage, and sample weighting and variability. Appendices include the student and institutional questionnaires. The guide has been prepared for and is available to interested researchers. (SB)