This study investigated the appropriateness both to the delivery system and to students of Athabasca University of the audiotutorial method of instruction in an introductory level Biology course, which used selections of audiotutorial materials from "Minicourses in Biology." Evaluation data were gathered by using pre-post test (content) results, time sheets, post cluster questionnaires (cognitive, affective, and instructional concerns), activity sheets, personal interviews, and credit examinations. Student enthusiasm was high, and a significant pre-post test improvement was evidenced in student achievement across clusters. Problem areas identified in the course included sequencing of clusters; clear differentiation to students of pre-, post-, and in-house laboratory activities; length of course; availability of packaged materials; and technical demands of delivery of live organisms in winter. This course, with appropriate modifications, was found suitable for offering to larger numbers of Albertans. (Author/JEG)