This manual, designed to help Head Start health coordinators effectively utilize the Early and Periodic Screening Diagnosis and Treatment (EPSDT) program, includes background on the development and goals of the EPSDT program and information gained during implementation of 200 EPSDT/Head Start demonstration projects. Chapter titles are: (1) Background and Historical Overview (History of Government Health Care Programs for Children, Brief Overview of EPSDT, The Head Start-EPSDT Collaboration); (2) Collaboration with State and Local Health and Welfare Agencies; (3) Collaboration with Local Providers; (4) Outreach; (5) Transportation; (6) Referral and Follow-up; (7) Record Keeping; (8) Reimbursement; (9) Model of a Small Community Head Start/EPSDT Program; and (10) Recipe Wrap-up (summary). (SB)