This report presents a preliminary series of investigations dealing with the detection of populations at psychological risk. The investigation relies primarily on the variable of vulnerability, as defined empirically by self-esteem, psychological discomfort, and social skills. Two vulnerability groups, high (HV) and low(LV) are compared on their psychophysiological and self-reported reactions to environmental stress as predictors of potential maladjustment. Finally, the description of a behavioral program for preventing the onset of disorder is presented. The techniques described were selected because of their specific relevance to those skill deficits identified in this particular group of high-risk adolescents. (Author)