A project to introduce PLATO IV computer-assisted instruction (CAI) in medical sciences education for health professionals was implemented at the School of Basic Medical Sciences at the University of Illinois. This paper describes the plan for evaluation of the project. Using a student questionnaire and additional general questions, the effectiveness of courseware materials will be assessed. Usage will be determined by the total hours spent with instructional materials and the number of sessions on the computer. Correlations will be calculated using test scores and hours of use on the appropriate lessons. If the number of total hours or total sessions separates students into two or more groups, analysis of variance will be conducted on the scores. The evaluation is intended to provide information for decision making and information for project personnel. (CH)