An experimental course in introductory organic chemistry at the University of Texas at Austin made use of the computer for drill and routine instruction. Lecturing time was reduced, and computer lessons were made part of the required coursework. This experimental situation was planned on the basis of results from previous experiments using computer-assisted instruction (CAI) in chemistry courses. Evaluation of student performance showed equivalence or improvement using the experimental approach compared to the traditional course. Student attitude surveys revealed support for the individual, self-paced, tutorial approach. Perceived disadvantages included time needed to complete computer-based lessons and difficulties with the computer system hardware. (CH)