In a study conducted to compare the results of two methods of instruction for the use of periodical, book, and newspaper indexes, the traditional lecture approach and self-study guide were investigated. Two library science classes were divided into two groups, and then divided further according to sex and class status. A self-study guide was formulated, for one group while the other group received the traditional lectures. A posttest was administered to both groups twelve days after formal instruction began, and the results were measured by a statistical analysis of variance test. The results verified the null hypothesis that no difference existed between the two groups; therefore, the lecture and self-study methods could be interchanged for instruction in the use of indexes. A table of estimated means and an analysis of variance table are included. The self-study guide for the project is appended. (Author/DS)