To determine whether contact with computer-assisted instruction (CAI) leads to feelings of "depersonalization" and "dehumanization" a review was conducted of investigations to explore attitudes toward various modes of computer-based instruction before, during, or after exposure. Evaluation of pertinent factors which influenced attitudes was made through assessment of relevant literature and personal communication with experts associated with CAI projects. Results of studies are compared in table form and recommendations made for future acceptance and implementation of computer-based systems. It is concluded that computer-based instruction is not a threat to humanization, and that it can provide opportunities for increasing effectiveness and personalization of the instructor-student relationship. (SK)