The nine-year history of the Computer Assisted Instruction Laboratory, College of Education, Pennsylvania State University, is traced. Some 30 projects in curriculum development in teacher education, public school classes, and adult vocational education are described, along with several advances in computer-assisted instruction (CAI). Interinstitution, intra-college, and intra-university cooperative efforts are defined. The laboratory's resources are detailed in terms of financial support, space, and staff. Some of the major issues facing the laboratory are briefly discussed, including the use of CAI in college instruction, sources of financial support, basic vs. applied research, and hardware systems development. Appendixes contain a chart which summarizes the Laboratory's CAI programs; a list of refereed publications by staff members; bibliographies of laboratory publications, applied research studies, and dissertations; a list of faculty participants; and the vitae of the principal investigators. (SK/JY)