This report, prepared by the National Clearinghouse for Drug Abuse Information, presents substantial information on the use and abuse of the drug "family" known as amphetamines. A brief history of the drug is given, along with its basic pharmacology. The current medical uses for amphetamines include: (1) short-term treatment of obesity, (2) treatment of the hyperkinetic syndrome, (3) treatment of narcolepsy, and (4) treatment of mild depression. The many nonmedical uses of these drugs are listed, along with the treatment process for overdoses and the amphetamine withdrawal syndrome. The legal status of those caught illicity using or selling these drugs is reviewed, along with other important issues and opinions on the topic. (Author/PC)