The report is the second in a series related to the problems of working effectively in cross-cultural interaction situations. The author develops a conceptual frame of reference for considering aspects of human nature that affect the interaction situation. Three keys to effective interaction are identified. It is argued that the selection and training of personnel for overseas assignments should be approached in terms of the conceptual frame of reference. Suggestions are made for further research on the development of an integrated personnel selection and training system. (Author)