This is the latest in a series of reported findings for a Guidance Study which followed the same persons from infancy to age 40. The report focuses on: (1) how well the 50 men and 60 women subjects maintained their positions relative to I.Q. during the 22 years since they were last tested at age 18; (2) gains and losses in I.Q. over the 22 year period; (3) characteristics of those who have gained or lost relative to the norm; and (4) the personality development of the subjects. Case-Q sort personality evaluations were used in relation to gains in I.Q. during adulthood and I.Q. at age 40. Results of the correlations are presented. The total group results suggest that those with high I.Q.'s are cognitively very able, are self-critical, introspective, not especially interested in other people, but are coping and highly thoughtful adults. Six individual cases are presented. Some general conclusions are consistent in pointing up the complexity of interacting factors which such studies must take into account. (TL)