Part of a larger study to formulate an economic development program for St. Louis, this document discusses the growth potential or expected decline of industry in the inner city; factors influencing the retention and the location of industries in greater St. Louis; and ways of stimulating new business, especially Negro owned businesses in the Target Area (TA). Also considered are deficiencies in education and training, commutation, and related difficulties of unemployed and underemployed TA residents; the role of the Federal government, industry, public schools, and private trade schools in occupational training; and patterns of commercial, industrial, and other land use, with projections of future demand in each category. Finally, a division of responsibility among TA neighborhood and community groups is suggested, together with the use of such planning techniques as economic accounting, statistical decision theory, and the systems approach to poverty programs. (ly)