AS PART OF A UNIVERSITY OF ROCHESTER EFFORT TO EXPLORE THE USE OF SELF INSTRUCTIONAL PROGRAMS AND MATERIALS IN EDUCATING DOCTORS, NURSES, PARAMEDICAL PERSONNEL, AND PATIENTS, THREE STUDIES OF PROGRAM UTILIZATION AND EFFECTIVENESS WERE MADE. DATA WERE OBTAINED ON COMPLETION AND NONCOMPLETION OF A PROGRAMED COURSE ON ALLERGIES, USER REACTIONS AS TO ITS USEFULNESS, AND ATTITUDES TOWARD THE USE OF MORE PROGRAMED MATERIALS. IN TWO STUDIES OF PROGRAMED INSTRUCTION IN CANCER DIAGNOSIS, TREATMENT, AND PATIENT MANAGEMENT, ACHIEVEMENT WAS MEASURED IN PROGRAMED AND CONVENTIONAL INSTRUCTION. IN THE ALLERGY PROGRAM, COURSE COMPLETIONS (87.5 PERCENT), POSITIVE REACTIONS (96 PERCENT), PERCEPTION OF PRACTICAL VALUE (93 PERCENT), AND FAVORABLE RESPONSES ON THE USE OF MORE PROGRAMED MATERIALS (95 PERCENT) INDICATED THAT EFFECTIVE PROGRAMED MATERIALS WOULD BE WELCOMED BY HEALTH PRACTITIONERS. IN THE CANCER PROGRAM, ACHIEVEMENT RESULTS SHOWED THAT PROGRAMED INSTRUCTION TAUGHT EFFECTIVELY AND IN A COMPARATIVELY SUPERIOR FASHION TO TRADITIONAL METHODS. (INCLUDED ARE FIVE TABLES, EIGHT REFERENCES, AND BACKGROUND DISCUSSION.) THIS PAPER WAS PRESENTED AT A NATIONAL SEMINAR ON ADULT EDUCATION RESEARCH (CHICAGO, FEBRUARY 11-13, 1968). (LY)