THE DEVELOPMENT AND COMPONENTS OF LYSERGIC ACID DIETHYLAMIDE (LSD) PRODUCED PSYCHOLOGICAL STATES ARE INVESTIGATED. THE SUBJECTS WERE PAID VOLUNTEERS FROM THE PATUXENT INSTITUTION, A TREATMENT CENTER FOR EMOTIONALLY UNSTABLE CRIMINAL OFFENDERS. IN ONE STUDY, GROUPS OF 23 SUBJECTS RECEIVED LSD, AN AMPHETAMINE, OR A PLACEBO. IN THE SECOND STUDY, 11 SUBJECTS RECEIVED CHLOROPROMAZINE. ADMINISTERED DOSES WERE MODEST. TESTS, REPEATED AT INTERVALS THROUGH THE DAY, CONSISTED OF SOMATIC MEASUREMENTS, AN ADAPTATION OF THE CLYDE MOOD SCALE, A SPECIALLY DEVELOPED SUBJECTIVE DRUG EFFECTS QUESTIONNAIRE, AND A NEW PICTURE RATING TECHNIQUE. AN EUPHORIC STATE WAS APPARENT IN SOME INDIVIDUALS, A DYSPHORIC STATE CHARACTERIZED SUBJECTS WHO WERE JITTERY, FEARED LOSS OF CONTROL, AND HAD IMPAIRED COGNITION. INDIVIDUALS IN AN AMBIVALENT STATE EXPERIENCED STRONG OPPOSING EMOTIONS AND PERCEPTIONS. THE MOST STRIKING OBSERVED EFFECTS WERE THE INTENSE EMOTIONS THESE SUBJECTS EXPERIENCED WITHOUT EXTERNAL STIMULUS. ALL LSD SUBJECTS EXPERIENCED PHENOMENA WHICH DISTINGUISHED THEM FROM PLACEBO AND AMPHETAMINE SUBJECTS. VARIOUS LSD PATTERNS PROBABLY RESULT FROM NON-DRUG FACTORS. THIS RESEARCH MAY CONTRIBUTE TO AN UNDERSTANDING OF HOW MORE PROFOUND LSD STATES BEGIN, BUT GENERALIZATIONS MUST BE LIMITED BECAUSE OF THE TYPE OF SUBJECTS USED. THIS ARTICLE IS A PREPRINT TO APPEAR IN THE JOURNAL OF ABNORMAL PSYCHOLOGY. (PR)