Background: The purpose of this study was to increase the body of knowledge regarding the workplace discrimination experiences of individuals with disabilities residing in the New England and Northeastern regions (NENR) of the United States by exploring their allegations filed under Title I of the Americans with Disabilities Act (ADA) across the universe of data from 1992 through 2016. Objective: Describe region- and state-level patterns in workplace discrimination and provide valuable information to stakeholders to better understand and address the issues within their respective areas of practice. Methods: Using population-level data from the Equal Employment Opportunity Commission's Integrated Mission System database, we analyzed every closed employment discrimination allegation filed under Title I of the ADA from January 26, 1992, through December 31, 2016. Descriptive statistics were obtained for each state within the NENR, with comparisons made on national and regional scales. Findings: The study presents state-level data across variables such as allegation type, charging party disability type, alternative prong allegations, and merit status of investigation outcomes. The results are organized into tables for ease of comparison, and suggested discussion questions for future exploration are provided. Conclusion: This study reveals notable variation in ADA Title I discrimination allegations across Northeastern states, highlighting the role of state-level factors in shaping workplace experiences. Findings offer actionable insights for policymakers, advocates, and service providers seeking to advance workplace inclusion and equity for individuals with disabilities across the region.