Objective: College students with attention deficit/hyperactivity disorder (ADHD) are at increased risk for numerous educational and psychosocial difficulties. This study reports findings from a large, multisite randomized controlled trial examining the efficacy of a treatment for this population, known as ACCESS -- Accessing Campus Connections and…

Aim: To describe the development of an intervention-specific fidelity measure and its utilization and to determine whether the newly developed Sitting Together and Reaching to Play (START-Play) intervention was implemented as intended. Also, to quantify differences between START-Play and usual early intervention (uEI) services. Method: A fidelity…

This paper reviews the use of multiple trials, defined as multiple sites or multiple arms in a single evaluation and replications, in evaluating social programs. After defining key terms, the paper discusses the rationales for conducting multiple trials, which include increasing sample size to increase statistical power; identifying the most…

The number of trials aimed at evaluating treatments for autism spectrum disorder has been increasing progressively. However, it is not clear which outcome measures should be used to assess their efficacy, especially for treatments which target core symptoms. The present review aimed to provide a comprehensive overview regarding the outcome…

Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…

Medical research is held as a field for education to emulate. Education researchers have been urged to adopt randomized controlled trials, a more "scientific" research method believed to have resulted in the advances in medicine. But a much more important lesson education needs to borrow from medicine has been ignored. That is the study…

Community colleges are essential for United States higher education, but their students have low retention and graduation rates. Community college students assigned to mathematics remediation are particularly unlikely to graduate. Corequisite remediation (college-level coursework with additional support) has shown short-term increased student…

Early intervention efforts have been effective in reducing disruptive behaviors and the probability of poor developmental outcomes. Early interventions include common practice elements to improve social functioning and decrease problem behaviors that disrupt the teaching-learning process. The First Step Next intervention has been well validated…

This paper examines the insistent claims by advocates of evidence-based teaching that it is a rigorous scientific approach. The paper questions the view that randomised controlled trials and meta-analyses are the only truly scientific methods in educational research. It suggests these claims are often based on a rhetorical appeal which relies on…

EBP -- evidence-based policy and practice -- has generated intense controversy. A rough continuum of positions can be discerned: At one pole are "tough-minded" commentators distinguished by their support of EBP; however, there are serious internal differences in this camp, for some regard randomised field trials (RFTs) as the gold…

Three phase 2 trials were conducted to assess the efficacy and long-term safety of weight-based memantine extended release (ER) treatment in children with autism spectrum disorder. MEM-MD-91, a 50-week open-label trial, identified memantine extended-release treatment responders for enrollment into MEM-MD-68, a 12-week randomized, double-blind,…

Theories regarding the long-term effects of educational interventions are often assumed, but rarely tested using experimental methods. In the following commentary, we argue that the shortage of randomized control trials with long-term follow-up presents serious problems for the field, as it hampers our ability to develop educational programs that…

There are a growing number of large-scale educational randomized controlled trials (RCTs). Considering their expense, it is important to reflect on the effectiveness of this approach. We assessed the magnitude and precision of effects found in those large-scale RCTs commissioned by the UK-based Education Endowment Foundation and the U.S.-based…

This study aims to evaluate the impact of a social cognitive theory (SCT)-based intervention on dietary behaviors and behavioral determinants. A randomized controlled trial was conducted with 230 adolescent girls (13-15 years old) in the intervention (n=115), and control group (n = 115), in Isfahan, Iran. Interventions were focused on changing SCT…

We report the feasibility and preliminary efficacy of a structured behavioral intervention with a sample of minimally verbal girls with autism spectrum disorder between the ages of 2 and 6 years old. Ten participants with no functional vocal behavior were randomized to a 4-week behavioral intervention or waitlist control group. Caregivers reported…