This research brief summarizes key lessons for college practitioners from a rigorous research study of a basic needs intervention. Single Stop is a program that colleges have used to assist with screening students to identify those eligible for such public benefits as the Supplemental Nutrition Assistance Program (SNAP) and Medicaid, make referrals to community resources, and support case management by college staff. In a randomized control trial of Single Stop across ten colleges in Colorado and North Carolina researchers struggled with student take-up of the supports. The main report leverages implementation data and student surveys to explain some of the barriers to implementation and take-up, and this research brief unpacks some of lessons learned from the study around how colleges might strengthen program implementation and take-up.