Background: Bloodstein reviewed hundreds of studies that investigated the efficacy of therapeutic protocols for ameliorating the stuttering syndrome. Surprisingly, almost all were effective in significantly reducing overtly perceptible behaviours such as repetitions and prolongations of speech sounds. These results seem highly improbable…

A recent development by neuroscience is neuroimaging, a method of looking into the "black box" of the brain while people are feeling, doing, and thinking in real time. The first fMRI study of bereavement has recently been published, and the present article summarizes it in non-specialist language, focusing on its theoretical and clinical…

Review of neurochemical investigations in autistic disorder revealed that a wide array of transmitter systems have been studied, including serotonin, dopamine, norepinephrine, acetylcholine, oxytocin, endogenous opioids, cortisol, glutamate, and gamma-aminobutyric acid (GABA). These studies have been complicated by the fact that autism is a very…

An understanding of the processing underlying single word reading will provide insight into how skilled reading is achieved, with important implications for reading education and impaired reading. Investigation of the functional neuroanatomy of both the mature and the developing systems will be critical for reaching this understanding. To this…

A neural theory of visual attention (NTVA) is presented. NTVA is a neural interpretation of C. Bundesen's (1990) theory of visual attention (TVA). In NTVA, visual processing capacity is distributed across stimuli by dynamic remapping of receptive fields of cortical cells such that more processing resources (cells) are devoted to behaviorally…

Serotonergic abnormalities have been reported in both autism and epilepsy. This association may provide insights into underlying mechanisms of these disorders because serotonin plays an important neurotrophic role during brain development--and there is evidence for abnormal cortical development in both autism and some forms of epilepsy. This…

Recent studies of redundancy gain indicate that it is especially large when redundant stimuli are presented to different hemispheres of an individual without a functioning corpus callosum. This suggests the hypothesis that responses to redundant stimuli are speeded partly because both hemispheres are involved in the activation of the response. A…

Objective: The objective of the present study is to replicate findings in first-episode psychosis reporting a smaller volume in brain structures in a population with adolescent onset. Method: Magnetic resonance imaging studies were performed on 23 psychotic adolescents (12-18 years old, 17 males, 6 females) consecutively admitted to an adolescent…

Gray matter volumes of Heschl's gyrus (HG), planum temporale (PT), pars triangularis (PTR), and pars opercularis were measured on MRI in 48 healthy right-handers. There was the expected leftward PT asymmetry in 70.8%, and leftward PTR asymmetry in 64.6% of the sample. When asymmetry patterns within individuals were examined, there was not one…

Neurological research has demonstrated that brain activity in animals originally dedicated to the production and regulation of physical activity can be decoupled from that physical activity. Furthermore, animals can use the brain activity in this new condition to achieve particular results such as moving a cursor on a screen. These findings are…

A common denominator for the induction of morphological and functional plasticity in cultured hippocampal neurons involves the activation of excitatory synapses. We now demonstrate massive morphological plasticity in mature cultured hippocampal neurons caused by a brief exposure to glutamate. This plasticity involves a slow, 70%-80% increase in…

This article provides a review and synthesis of concepts, research programs, and measures in the infant and child temperament area. First, the authors present an overview of five classical approaches to the study of child temperament that continue to stimulate research today. Subsequently, the authors carve out key definitional criteria for…

Velo-cardio-facial syndrome (VCFS) has been in the focus of intensive research over the last 15 years. The syndrome represents a homogeneous model for studying the effect of a decreased dosage of genes on the development of brain structure and function and, consequently, on the emergence of schizophrenia-like psychotic disorder. In this review, we…

This study describes the development of a Minnesota Multiphasic Personality Inventory (MMPI-2) scale designed to detect negative response bias in forensic neuropsychological or disability assessment settings. The Response Bias Scale (RBS) consists of 28 MMPI-2 items that discriminated between persons who passed or failed the Word Memory Test…

Neuropsychological functioning of 30 siblings of children with autism (AU-S), 28 siblings of children with mental retardation of (MR-S), and 30 siblings of children with developmental language delay (DLD-S) was compared. Two siblings, both AU-S, received diagnoses of pervasive developmental disorder (PDD). More siblings with cognitive disabilities…