This paper reviews literature supporting the notion that learning disabilities are presumed to be a result of central nervous system dysfunction. It focuses on the postmortem and neuroimaging studies that provide evidence of a neurological conceptualization of learning disabilities. (Author/JDD)

Neural network technology was compared with simultaneous and stepwise linear discriminant analysis in terms of their ability to classify and predict persons (n=138) as having autism or mental retardation. The neural network methodology was superior in both classifying groups and in generalizing to new cases that were not part of the training…

Argues that the brain is the seat of cognition, that cognitive processes are neutral processes, and that, in the brain, affect and cognition are distinguishable but inseparable. This perspective allows a reconceptualization of the affective filter in terms of the brain's stimulus appraisal system, which interacts with cognition to promote or…

A theory of neurolinguistic function is proposed to explain fluency and the production of stuttered speech disruptions. Stuttering results when the speaker is under time pressure and is unaware of the cause of dyssynchrony between the linguistic and paralinguistic components of speech which are processed by different neural systems but converge on…

In the 1930s, Bernstein pointed out that more than one motor signal can trigger the same physical movement and that identical motor signals can lead to different movements, a dilemma that continues to puzzle scientists. Based on results from computer simulations, posits that these motor signals can be grouped into categories that correspond to…

Introduces the construct of habits on a continuum from habit impoverishment to habit domination. Introduces the concepts of thresholds for action, modulation, and motivation to reestablish homeostasis and proposes a model for interpreting behavior. Explains patterns of responding in relation to adaptive and maladaptive behavior. (Contains 36…

Examines a subset of tools (atlases of the brain) developed in the Human Brain Project (HBP) in order to understand how the use of these tools changes the practice of science. Discusses the redefinition of what constitutes 'objective' neuroscientific knowledge according to both technological possibilities built into these tools and the constraints…

Used functional magnetic resonance imaging (fMRI) to examine spatial working memory in 8- to 11-year-olds tested under 3 conditions. Found that subtracting activation of the motor condition from the memory condition revealed activity in dorsal aspects of the prefrontal cortex and in the posterior parietal and anterior cingulate cortex. Analysis of…

The discipline of neuroscience draws from the fields of neurology, psychology, physiology and biology, but is best understood in the wider world as brain science. Of particular interest for education is the development of techniques for imaging the brain as it performs different cognitive functions. Cognitive neuroimaging has already led to…

New positron emission tomography (PET) and MRI technologies, which allow looking inside the brains, show that the brains of boys and girls differ both structurally and functionally that profoundly affect the human learning. These gender differences in the brain are corroborated in males and females throughout the world and do not differ…

Autobiographical remembering reflects an advanced state of consciousness that mediates awareness of the self as continuous across time. In naturalistic autobiographical memory, self-aware recollection of temporally and spatially specific episodes and generic factual information (both public and personal) operate in tandem. Evidence from both…

There is a wide range of functional magnetic resonance imaging (fMRI) study designs available for the neuroscientist who wants to investigate cognition. In this manuscript we review some aspects of fMRI study design, including cognitive comparison strategies (factorial, parametric designs), and stimulus presentation possibilities (block,…

Neuroelectric and imaging studies of meditation are reviewed. Electroencephalographic measures indicate an overall slowing subsequent to meditation, with theta and alpha activation related to proficiency of practice. Sensory evoked potential assessment of concentrative meditation yields amplitude and latency changes for some components and…

Having recently shown that extinction of conditioned fear depends on L-type voltage-gated calcium channels (LVGCCs), we have been seeking other protocols that require this unusual induction mechanism. We tested latent inhibition (LI) of fear, because LI resembles extinction except that cue exposures precede, rather than follow, cue-shock pairing.…

We discuss the relationship between sleep, dreams, and memory, proposing that the content of dreams reflects aspects of memory consolidation taking place during the different stages of sleep. Although we acknowledge the likely involvement of various neuromodulators in these phenomena, we focus on the hormone cortisol, which is known to exert…