Decision makers and strategy leaders in states often lack the information they need to make decisions that will support learners' success. Many lack information on what data their states already collect and publicize, and many are unsure of what data might tell a more meaningful story about student success. Responding to this need, researchers and data experts came together to design the Education-to-Workforce Indicator Framework (E-W Framework), which aims to advance educational and economic opportunity for all through better data collection and use. The framework and its associated implementation tools provide research-based guidance for constructive conversations about how to enhance data collection efforts across agencies and offices within a state. The E-W Framework offers principles for ethical and effective data use, essential questions and indicators that matter most, ways to disaggregate data to inform action, and evidence-based practices to drive positive change. A core component of the framework is the essential questions, which are questions state leaders often need to answer to understand how students are progressing from early education through their careers. This Special Report will introduce the E-W Framework, offer a process for identifying the essential questions, help create or refine the data collection approach, and offer strategies for acting on the answers data systems provide.