This paper explores the implementation of gamification in higher education, specifically within the anatomy and physiology classroom. By leveraging desirable game elements, such as rapid feedback, a low-stakes environment, and collaborative learning, educators may enhance student engagement, persistence, and overall learning experiences. I will discuss key components for successful gamification, including clarity, accessibility, and atmosphere creation, while also addressing potential barriers such as student preferences and perceptions of acceptable methods. Five innovative gamification strategies--Jenga, Headbands, Acid-Base Race, Team (Bone) Building, and a Physiology Space Race--are presented as practical applications to build an interactive and enjoyable learning environment. Additionally, we emphasize the need for further research to evaluate the effectiveness of gamification in promoting student retention and a sense of belonging in STEM fields. Ultimately, gamification can serve as a valuable instructional strategy in anatomy and physiology, transforming the classroom into a more dynamic, positive and inclusive space.