[alpha]CaMKII[superscript T286A] mutant mice lack long-term potentiation (LTP) in the hippocampal CA1 region and are impaired in spatial learning. In situ hybridization confirms that the mutant mice show the same developmental expression of [alpha]CaMKII as their wild-type littermates. A simple hypothesis would suggest that if LTP is a substrate…

It is known from studies outside the brain that upon binding to its receptor, angiotensin-(1-7) elicits the release of prostanoids and nitric oxide (NO). Cyclooxygenase (COX) is a key enzyme that converts arachidonic acid to prostaglandins. Since there are no data available so far on the role of COX-2 in the amygdala, in a first step we…

Virtual environments, such as online games and web-based chat rooms, increasingly allow us to alter our digital self-representations dramatically and easily. But as we change our self-representations, do our self-representations change our behavior in turn? In 2 experimental studies, we explore the hypothesis that an individual's behavior conforms…

Design briefs are plausible situations in which students are asked to solve problems given limited materials, a specific time frame, and a number of rules and limitations. It is the author's contention that the design brief, an established format in technology education, can serve as a unique approach to extend and assess everyday science…

We conducted four experiments to examine developmental differences in preferences for using color, size, and location information to disambiguate hiding places. Three- and 4-year-olds and adults described how to find a miniature mouse that was hidden in one of two highly similar small objects in a dollhouse. In Experiment 1, the hiding places…

Infrared thermal imaging is a valuable tool in physics education at the university level. It can help to visualize and thereby enhance understanding of physical phenomena from mechanics, thermal physics, electromagnetism, optics and radiation physics, qualitatively as well as quantitatively. We report on its use as lecture demonstrations, student…

The purpose of this article is to describe a simple laboratory activity in which students collect a series of measurements and then use graphical analysis to determine the nature of the relationship between an object's mass and the volume of water it displaces. In this activity, students explore the relationships between the mass of a floating…

The authors bring together two research streams in the literature that examine separately the effectiveness of using experiments in the principles classroom and the relationship between different personality types and student achievement. Using a sample of 255 principles of microeconomics students, 48 of whom were enrolled in sections that relied…

In our college course, "Life Science for Elementary School Teachers," our investigation assesses the germination success of an invasive plant, purple loosestrife, compared to native wildflowers. Topics addressed include the scientific method, experimental design, seed dormancy, plant competition, ethno-botany, and success of non-native plants. The…

This study used an experimental paradigm to investigate the role of secondary cognitive appraisals in women's sexual assault resistance and whether these appraisals mediated influences of alcohol and prior victimization. After consuming a beverage (control, placebo, moderate, or high dose), 351 women projected themselves into a simulated…

National studies of science education have unanimously concluded that preparing our students for the demands of the 21st century workplace is one of the major goals. This paper describes a study of student activities in introductory college physics labs, which were designed to help students acquire abilities that are valuable in the workplace. In…

The series of experiments proposed for advanced undergraduate students deal with both standard organometallic preparative methods in dry anaerobic conditions and with a kinetic study of the mechanisms operating in the substitution of square-planar complexes. The preparation of organometallic compounds is carried out by transmetallation or…

An experiment to determine the rotational barrier about a C[subscript aryl]-N[subscript imide] single bond that is suitable for first-semester organic chemistry students is presented. The investigation begins with the one-step synthesis of a N,N'-diaryl naphthalene diimide, which exists as two room temperature-stable atropisomers (syn and anti).…

A laboratory experiment is presented in which the freezing point depression is analyzed using milk as solution. The nature of milk as a mixture of different solutes makes it a suitable probe to learn about colligative properties. The first part of the experiment illustrates the analytical use of freezing point measurements to control milk quality,…

An experiment for the undergraduate chemistry laboratory in which students perform the aldol condensation on an unknown aldehyde and an unknown ketone is described. The experiment involves the use of techniques such as TLC, column chromatography, and recrystallization, and compounds are characterized by [to the first power]H NMR, GC-MS, and FTIR.…