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Peer reviewed
Direct linkLopes, O.; Barton, G.; Morgan, J. – Journal of Intellectual Disability Research, 2005
The clinical features of this rare chromosomal syndrome are described in two individuals. Our limited knowledge of the natural history of this disorder has made it difficult to counsel parents as well as outline specific treatment and management plans. Interviews were undertaken with subjects, carers and next of kin, and the literature was…
Descriptors: Clinical Diagnosis, Genetics, Interviews, Physical Disabilities
Mustapha, Y.; Muhammad, S. – Educational Research and Reviews, 2006
The assembly of proteins takes place in the cytoplasm of a cell. There are three main steps. In initiation, far left, all the necessary parts of the process are brought together by a small molecule called a ribosome. During elongation, amino acids, the building blocks of proteins, are joined to one another in a long chain. The sequence in which…
Descriptors: Genetics, Science Education, Cytology, Molecular Biology
Bandopadhyay, Rina; Kingsbury, Ann E.; Cookson, Mark R.; Reid, Andrew R.; Evans, Ian M.; Hope, Andrew D.; Pittman, Alan M.; Lashley, Tammaryn; Canet-Aviles, Rosa; Miller, David W.; McLendon, Chris; Strand, Catherine; Leonard, Andrew J.; Abou-Sleiman, Patrick M.; Healy, Daniel G.; Ariga, Hiroyashi; Wood, Nicholas W.; de Silva, Rohan; Revesz, Tamas; Hardy, John A.; Lees, Andrew J. – Brain, 2004
Two mutations in the DJ-1 gene on chromosome1p36 have been identified recently to cause early-onset, autosomal recessive Parkinson's disease. As no information is available regarding the distribution of DJ-1 protein in the human brain, in this study we used a monoclonal antibody for DJ-1 to map its distribution in frontal cortex and substantia…
Descriptors: Diseases, Brain, Neurology, Neurological Impairments
Hermann, Gilbert – American Biology Teacher, 2003
Molecular genetics is a rapidly changing field with new developments almost from day to day. One interesting hypothesis that has come from everyone's ability to sequence proteins and/or genes is that of the molecular clock. This hypothesis postulates that homologous sequences of DNA and thus macro molecules evolve at a constant and invariable rate…
Descriptors: Genetics, Evolution, Molecular Biology, Science Instruction
Nettle, Daniel – American Psychologist, 2006
A comprehensive evolutionary framework for understanding the maintenance of heritable behavioral variation in humans is yet to be developed. Some evolutionary psychologists have argued that heritable variation will not be found in important, fitness-relevant characteristics because of the winnowing effect of natural selection. This article…
Descriptors: Biodiversity, Personality, Evolution, Genetics
Greve, Werner; Ebner, Natalie C. – European Journal of Developmental Science, 2007
Is human ontogenesis a product of evolution or a result of individual decisions and actions? In the present paper we aim at solving this apparent conflict between a behavioral genetics approach and an action-theoretical perspective to human development. After a discussion of the idea of active and intentional self-development and the role of genes…
Descriptors: Individual Development, Evolution, Behavior Development, Genetics
Rosenblatt, Jay S. – European Journal of Developmental Science, 2007
In addition to his pioneering studies on prenatal development of social responses in the mallard, Gilbert Gottlieb made important theoretical contributions to the study of the evolution of behavior. This tribute to Gottlieb presents his early view that prenatal behavioral development is the product of evolution and his revision of this view in his…
Descriptors: Prenatal Influences, Individual Development, Genetics, Evolution
Scheithauer, Herbert; Niebank, Kay; Gottlieb, Gilbert – European Journal of Developmental Science, 2007
The aim of Developmental Science is to understand the complex interacting biopsychosocial mechanisms in the development of living organisms. Thus, Developmental Science has roots in both the biological and social disciplines and can bee seen as a meta-theory rooted in developmental principles to guide work and thinking on biology and social…
Descriptors: Developmental Psychology, Biology, Social Sciences, Social Behavior
Din, Neena; Bird, Terry H.; Berleman, James E. – American Biology Teacher, 2007
In this article, the authors present a laboratory activity that relies on the use of a very versatile bacterial system to introduce the concept of how mutagenesis can be used for molecular and genetic analysis of living organisms. They have used the techniques of random mutagenesis and selection/screening to obtain strains of the organism "R.…
Descriptors: Science Laboratories, Genetics, Botany, Science Activities
Krist, Amy C.; Showsh, Sasha A. – American Biology Teacher, 2007
Evolution is typically measured as a change in allele or genotype frequencies over one or more generations. Consequently, evolution is difficult to show experimentally in a semester-long lab course because most organisms have longer generation times than 15 weeks. In this article, the authors present an experiment to demonstrate and study…
Descriptors: Evolution, Microbiology, Science Instruction, Teaching Methods
Miller, Roxanne Greitz – Science Scope, 2007
If we abide by the familiar saying "you are what you eat," it is understandable that people may be concerned with the incredible advances in food science technology and their possible impacts on human health. For example, in recent years high-tech scientific processes such as genetic modification, irradiation, and cloning have all been used to…
Descriptors: Safety, Foods Instruction, Science Instruction, Technological Advancement
Hall, Scott S.; Burns, David D.; Reiss, Allan L. – Journal of Abnormal Child Psychology, 2007
Few studies have examined the impact of children with genetic disorders and their unaffected siblings on family functioning. In this study, the reciprocal causal links between problem behaviors and maternal distress were investigated in 150 families containing a child with fragile X syndrome (FXS) and an unaffected sibling. Both children's…
Descriptors: Children, Genetics, Congenital Impairments, Siblings
Baker, Harold H. – Exceptional Parent, 2007
Byron Seibold recently celebrated his 70th birthday, which is not a remarkable milestone in today's era of extended longevity. Mr. Seibold has the typical maladies of aging--some vision and hearing issues, a bad hip, some memory lapses but no signs of Alzheimer's. His primary care physician, Dr. Chris Prater, attributes Mr. Seibold's good health…
Descriptors: Dementia, Physicians, Down Syndrome, Genetics
Clifford, Sally; Dissanayake, Cheryl; Bui, Quang M.; Huggins, Richard; Taylor, Annette K.; Loesch, Danuta Z. – Journal of Autism and Developmental Disorders, 2007
The behavioural phenotype of autism was assessed in individuals with full mutation and premutation fragile X syndrome (FXS) using the Autism Diagnostic Observation Scale-Generic (ADOS-G) and the Autism Diagnostic Interview (ADI-R). The participants, aged 5-80 years, comprised 33 males and 31 females with full mutation, 7 males and 43 females with…
Descriptors: Genetics, Diagnostic Tests, Autism, Mental Retardation
van Lier, Pol; Boivin, Michel; Dionne, Ginette; Vitaro, Frank; Brendgen, Mara; Koot, Hans; Tremblay, Richard E.; Perusse, Daniel – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To examine whether kindergarten children's genetic liability to physically aggress moderates the contribution of friends' aggression to their aggressive behaviors. Method: Teacher and peer reports of aggression were available for 359 6-year-old twin pairs (145 MZ, 212 DZ) as well as teacher and peer reports of aggression of the two best…
Descriptors: Twins, Aggression, Prevention, Risk
