Examines the role of cerebrospinal fluid (CSF), a clear, colorless liquid that constantly bathes the brain and spinal cord. Scientists argue that cerebrospinal fluid carries important signals for sleep, appetite, and sex. Evaluates past and current research documenting the purpose of cerebrospinal fluid in the brain. (CCM)

Explores the nature of knowledge, particularly the difference between genetic knowledge and cultural knowledge, and its significance for understanding evolution. This exploration is the foundation of a discussion on medical information inherited in genes and accumulated in society. The problems of cultural medical knowledge for evolution are…

Describes how to gain optimal learning in the classroom by activating different parts of the brain. Neural systems fatigue very quickly and need to rest. Only a few minutes of factual lecture can be tolerated before the brain seeks other stimuli. The most effective presentation must move back and forth through interrelated neural systems, weaving…

Investigates differences in brain structures, as reflected in hemispheric laterality, and sex on communicator style preferences. Combines handedness, familial sinistrality, and related correlates as a predictor of standard or anomalous hemispheric dominance. Finds data consistent with hypothesis that communication preferences have a…

The nature of the representations maintained in verbal working memory is a topic of debate. Some authors argue for a modality-dependent code, tied to particular sensory or motor systems. Others argue for a modality-neutral code. Sign language affords a unique perspective because it factors out the effects of modality. In an fMRI experiment, deaf…

Humans are fast and accurate at performing an animal categorization task with natural photographs briefly flashed centrally. Here, this central categorization task is compared to a three position task in which photographs could appear randomly either centrally, or at 3.6 [degrees] eccentricity (right or left) of the fixation point. A mild…

In this study, we investigated whether the left and right hemispheres are differentially involved in causal inference generation. Participants read short inference-promoting texts that described either familiar or less-familiar scenarios. After each text, they performed a lexical decision on a letter string (which sometimes constituted an…

Many studies in visual face recognition have supported a special role for the right fusiform gyrus. Despite the fact that faces can also be recognized haptically, little is known about the neural correlates of haptic face recognition. In the current fMRI study, neurologically intact participants were intensively trained to identify specific…

Event-related brain potentials (ERPs), judgment accuracy, and reaction times (RTs) were obtained for 11 adults who stutter and 11 normally fluent speakers as they performed a rhyme judgment task of visually presented word pairs. Half of the word pairs (i.e., prime and target) were phonologically and orthographically congruent across words. That…

The functional link between the amygdala and hippocampus in humans has not been well documented. We examined the effect of unpleasant loud noise on hippocampal and amygdaloid activities during picture encoding by means of fMRI, and on the correct response in humans. The noise reduced activity in the hippocampus during picture encoding, decreased…

This paper examines the impact of auditory deprivation and sign language use on the enhancement of location memory and hemispheric specialization using two matching tasks. Forty-one deaf signers and non-signers and 51 hearing signers and non-signers were tested on location memory for shapes and objects (Study 1) and on categorical versus…

In this paper we attempt to relate the prelexical processing of speech, with particular emphasis on functional neuroimaging studies, to the study of auditory perceptual systems by disciplines in the speech and hearing sciences. The elaboration of the sound-to-meaning pathways in the human brain enables their integration into models of the human…

The cortical regions of the brain traditionally associated with the comprehension of language are Wernicke's area and Broca's area. However, recent evidence suggests that other brain regions might also be involved in this complex process. This paper describes the opportunity to evaluate a large number of brain-injured patients to determine which…

Numerous brain areas work in concert to subserve memory, with distinct memory functions relying differentially on distinct brain areas. For example, semantic memory relies heavily on posterior cortical regions, episodic memory on hippocampal regions, and working memory on prefrontal cortical regions. This article reviews relevant findings from…

There is incomplete consensus on the anatomical demarcation of Broca's area in the left inferior frontal gyrus and its functional characterization remains a matter of debate. Exclusive syntactic specialization has been proposed, but is overall inconsistent with the neuroimaging literature. We examined three functional MRI (fMRI) datasets on…