Using the biochemical record to class archaebacteria, eukaryotes, and eubacteria involves abstractions difficult for the concrete learner. Therefore, a method is provided in which students discover some basic tenets of biochemical classification and apply them in a "hands-on" classification problem. The method involves use of RNA…

Determined whether or not formative evaluation could facilitate goal attainment in a biochemistry course and produce desired learning outcomes consistently by altering course materials and/or instruction. Formative evaluation procedures included two tests administered to subjects (N=64) over a three-year period. Findings supported the formative…

Described is an advanced undergraduate kinetics experiment using buffer dilutions to determine spontaneous rate, catalyzed rate, and reaction order. The reaction utilized is hydrolysis of p-nitro-phenyl acetate in presence of imidazole, which has been shown to enhance rate of the reaction. (Author/JN)

Suggests the topic of macromolecules and synthetic polymers be included in undergraduate courses. Two macromolecular systems (polyethylene in a state unperturbated by long-range interactions and a polypeptide undergoing a helix-coil transition) are described which are suitable for inclusion in the statistical mechanics section of physical…

Describes procedures and semi-micro reaction apparatus (carbon dioxide trap) to demonstrate how a particular enzyme (L-Glutamic acid decarboxylase) may be used to determine the site or sites of labeling in its substrate (carbon-14 labeled glutamic acid). Includes calculations, solutions, and reagents used. (Author/SK)

Presented is one of a series of articles designed to help science teachers keep current on ideas in specific areas in biology. Contained is information on how plants use light for growth, seed germination, and flowering. (PB)

The concept of stereochemical nonequivalence (heterotopicity) of apparently identical ligands, or of apparently identical faces, is discussed. (HM)

Describes some basic findings in the radiation chemistry of genetic material derived from studies of model systems. Uses these findings to extrapolate the consequences of radiation damage to DNA within cells. (CS)

Discusses the effects of radiation on dividing cells and factors influencing these effects; also briefly reviews the radical mechanism for radiation damage. Emphasizes the importance of oxygen in radiation effects. (CS)

Popular culture now considers marijuana harmless, but research shows it has definite physiological and neurological effects, effacing memory and attention and producing cell damage and learning deficits. Young people turn to pot to escape the emotional pressures of adolescence. Parents and schools can help adolescents by setting firm prohibitions.…

Discussed is the nature of cyanide poisoning. Included are sources of the cyanide ion, the mechanism of poisoning, the biochemical basis for treatment, and therapeutic measures. (BT)

An approach to enzyme kinetics which emphasizes similarities between equilibrium binding and steady state kinetics is outlined. It is intended for use in teaching biochemistry to beginning students. (Author/SA)

This undergraduate biochemistry experiment introduces the student to techniques for cell lysis and release of protein from the cell in soluble form, ion exchange and gel chromatography, and dialysis. (Author/BB)

This experiment can be used as either a demonstration or a laboratory activity illustrating the principles of affinity chromatography to purify an enzyme. (BB)

Antianxiety agents are discussed in terms of their effects on the brain and central nervous system. Formulas for some substances, commonly prescribed as sedatives, are given. Includes a discussion on the toxicity and side effects of the drugs. (SA)