Describes an exercise that extends the actual determination of the amino acid sequence of a simple dipeptide to the theoretical determination of the complete primary structure of a larger polypeptide. Includes diagrams of display cards and duplicated sheets used in the theoretical portion of the exercise. (CS)

Proposes an examination of the motives in having biochemistry students perform practical laboratory exercises. Suggests that a typical course should be viewed as a progression of skills development culminating in a final year, open-ended research project that demands that the skills be used competently and efficiently. (DDR)

Nineteen hospitalized, emotionally disturbed boys screened for maltreatment either before or after age 3 were compared with a normal control group for enzyme activity and conscience functions in moral valuation. Subjects who experienced early maltreatment had more developmental delays and more interferences with conscience functions than other…

Describes an integrated approach to teaching a biochemistry laboratory focusing on the relationship between the three-dimensional structure of a macromolecule and its function. RNA is chosen as the model system. Discusses curriculum and student assessment. (AIM)

Presents an activity that aims at enabling students to recognize that DNA and RNA are information molecules whose function is to store, copy, and make available the information in biological systems, without feeling overwhelmed by the specialized vocabulary and the minutia of the central dogma. (JRH)

This study, with 43 boys ages 8-12, found that children with relatively high concentrations of lead in their hair reacted significantly slower in a simple reaction-time task than did children with relatively low concentrations of lead in their hair. In addition, the former were significantly less flexible in changing their focus of attention.…

This paper reviews the effects of iodine deficiency across the lifespan, with special reference to mental defect; discusses the magnitude of the problem; describes available iodine technology to control iodine deficiency disorders (IDD); and notes the status of national IDD control programs, to assess the likelihood of eliminating IDD by the year…

A single, didactic criterion for the description of all biological macromolecules is proposed. This criterion is applicable to globular, fibrous or mixed proteins, as well as to nucleic acids and lipids or polysaccharides. Specific examples are given for all except lipids and polysaccarides. (KR)

The Briggs-Haldane assumption is used as the basis for the development of a kinetic model for enzyme catalysis. An alternative definition of the steady state and examples of realistic mechanisms are provided. (KR)

Of 806 institutionalized adults with mental retardation, 15.5 percent exhibited pica. Fifty-four percent of the pica group had serum zinc levels below normal range, whereas 7 percent of a control group had serum zinc levels below the normal range. After supplementation with chelated zinc, residents had significant reductions in pica. (Author/JDD)

Described is the "typical" curriculum necessary for graduation with a biochemistry degree from college. The information was synthesized from over 600 responses to a questionnaire sent to colleges and universities. Biochemical educators and scientists have been asked to review the curriculum and send comments. (KR)

Evaluates the traditional method of intercalating theoretical and seminar classes with laboratory practical work. Proposes a new schedule where students get problem-based learning of theoretical concepts during the first half of the course, and plan and execute a laboratory project during the second half. (Author/CCM)

Recommends utilizing biochemistry problems to develop students' abilities to clearly identify the relevant questions hidden in problematic situations and to select the information required to solve them. This procedure is highly motivating and offers students a tool for evaluating their achievements. (Author/CCM)

Examines the responses of senior academic biochemists to an incident of scientific wrongdoing. Concludes that these individuals endorsed less-formal action when either the actions were believed to have the potential to publicly embarrass the offending individual, or when the actions might adversely affect the professional career of the…

Describes the use of a theoretical framework of DNA topology and a simple method for modeling structures as successful ways of teaching students about DNA supercoiling. (WRM)