The main objective of this class experiment is to measure the activity of two metabolic enzymes in crude extract from bird pectoral muscle and to relate the differences to their mode of locomotion and ecology. The laboratory is adapted to stimulate the interest of wildlife management students to biochemistry. The enzymatic activities of cytochrome…

CF-1 male mice were trained in an inhibitory avoidance task using a high footshock (1,2 mA, 50 Hz, 1 sec) in order to reduce the influence of extinction on retention performance. At 2, 7, 14, or 30 d after training, the first retention test was performed and hemicholinium (HC-3, 1.0 microgram/mice), a specific inhibitor of high-affinity choline…

We examined the relationship between stress hormone (cortisol) release and acquisition and consolidation of conditioned fear learning in healthy adults. Participants underwent acquisition of differential fear conditioning, and consolidation was assessed in a 24-h delayed extinction test. The acquisition phase was immediately followed by an 11-min…

The arrangement of course information in a logical sequence for molecular life science (MLS) courses remains a matter of some controversy, even within a single subdiscipline such as biochemistry. This is due to the explosion of knowledge, the latest bioinformatic revelations, and the observation that new discoveries sometimes reveal specific…

Information in the nervous system is conveyed by impulses called action potentials: large, transient electrochemical changes in a neuron's membrane. Though action potentials are a basic feature of neurons, teachers often have trouble explaining this neurophysiological concept, and students have difficulty understanding it. While easy-to-understand…

Describes a set of biochemistry laboratory experiments in which tetrameric hemoglobin is separated into its subunits then formed again by recombination of the subunits. (MLH)

Questions and answers to biochemistry four topics are presented. Items include fatty acid synthesis, reaggregation of sponge cells, enzymic degradation of pollutants, and energy requirements of organisms. (RWH)

Describes the initially ignored research performed in 1900 by Archibald Garrod concerning the link between heredity and biochemical reactions. (MLH)

This review examines the available evidence in support of the argument that serum uric acid (SUA) possesses considerable promise as an indicator of one type of biochemical influence on achievement behavior. The evidence arguing for further research into the role of serum cholesterol in achievement behavior is also examined. (Author/JR)

Sequential urinalysis of four premature infants with marked physiologic anemia demonstrated no erythropoietin (substances which may stimulate red blood cell formulation). (CL)

Levels of serum IgE (an immunoglobulin carrying reaginic antibody activity) were investigated in 16 Down's syndrome adolescents (12-to 18-years old) and in an equal number of retardates matched for age and sex residing in the same institution. (CL)

This paper presents an overview of the functions of connective tissue and the mechanisms of joint injury and contracture formation in relation to therapeutic exercise. The components of connective tissue operation are explained, including fibroblasts, macrophages, plasma cells, and collagen. An examination of the histology of connective tissue as…

Describes a system for the management and analysis of chemical structure-biological activity data wherein the chemical structures, encoded in Wiswesser Line Notation, are checked for accuracy, stored, and retrieved by computer. Unification of description and activity of bio-systems. Structuring data files. (Author)

Six 4- to 37-year-old patients with tuberosis sclerosis (a chronic condition characterized by siezures, intercranial calcification, a reddish-yellow sebaceous glandular mass on the face, and frequent crises in early years), did not exhibit an elevation of the (alpha + beta) globulin fraction in their serum. (Author/MC)