Studied were three unrelated infants with distal renal tubular acidosis (a condition characterized by an inability to acidify the urine to minimal pH levels resulting in the loss of bicarbonates). (DB)

Prenatal monitoring for metachromatic leukodystrophy (a fatal inherited metabolic disorder) suggested that the determination of levels of cerebroside sulfatase in the amniotic fluid helped in the prenatal detection of this disorder. (DB)

This article is designed to inform chemical educators not engaged in this technology as to the nature and methods used in the technology, the reasons for scientific and social concern, and the attempts made to assuage concerns involving recombinant DNA research. (author/BB)

Mendeleev's prediction of existence of the radioactive element, Polonium, and the discovery of iproniazid and its role in antidepressant therapy are presented. (BB)

Serum immunoglobulin levels were measured in 20 patients with Down's syndrome (mean age 23 years) and 16 mentally retarded cerebral palsy control patients (mean age 25 years). (Author)

A brief discussion of neurophysiology, neurotransmitters, and the effect of psychoactive drugs on brain diseases such as schizophrenia. (BB)

Some newly reported research results indicate that slightly abnormal biological rhythms, both long- and short-term, may be key factors in the development of depression and manic-depression. The results may also hold clues about why certain drugs work or fail to work with different individuals. (Author/BB)

Discusses different foods with reference to oxidation and energy production. Amino acid assays are provided for eggs, steak, rice, and lentils and white and dark turkey meat is analyzed for energy and power outputs. (MA)

Recent studies done by federal researchers indicate that human aggression may be affected by a critical balance of two or three key brain chemical neurotransmitters. Results of this study with human beings are included in this article. (MA)

The author explains that misunderstanding the role of science and scientists is mainly due to a communication gap precipitated by the enormity of the field of science. Among the many examples given are cloning and DNA from biomedical research. Argues strongly against establishing an agency to control the field of scientific research. (GA)

A discussion is presented of the toxicity, chemistry, and environmental presence of nitrosamines. Carcinogenicity and effects on various organs of test animals are reviewed. Also some information on the presence of use of nitrosamines in human food is given. (MR)

A plant protoplast is basically a plant cell that lacks a cell wall. This article outlines some of the ways in which protoplasts may be used to advance understanding of plant cell biology in research and student instruction. Topics include high efficiency experimental virus infection, organelle isolation, and osmotic effects. (Author/MA)

Reviews much of what is known about microtubules, which are biopolymers consisting predominantly of subunits of the globular protein, tubulin. Describes the functions of microtubules, their structure and assembly, microtube associated proteins, and microtubule-disrupting agents. (TW)

Cocaine and nicotine are among stiumulants used by athletes to improve their performance or for escape. Negative effects of these stimulants are discussed. (Author/CB)