The concentration of the primary brain metabolite of norepinephrine is diminished in the lumbar spinal fluid of patients with Korsakoff's syndrome. The extent of its reduction is correlated with measures of memory impairment. (BB)

Describes the unicellular microorganisms of three billion years ago. Explains how these primitive cells gave rise to biochemical systems and the present oxygen-rich atmosphere. Numerous diagrams, charts, and illustrations. (MA)

Behavioral effects of L-5-Hydroxytryptophan (L-5-HTP), administered in combination with carbidopa, were evaluated in three autistic children (4-8 years old) using direct behavioral observation and parent ratings. (Author)

Presents the schedule of American Physiological Society (APS) sponsored and cosponsored symposia to be held at the Spring 1978 APS meeting. There are twenty-two symposia scheduled over a four-day period. (BB)

The current president of the National Academy of Science (NAS) is interviewed in this article. He discusses the reorganization of NAS and the National Research Council during his term of office. Concerns over environmental science, biochemistry research, and the decreasing role of science advisors to the Pentagon are presented. (MA)

Discusses the relationship of the central monoamine (MA) serotinin (5 hydroxytryptamine or 5 HT) and certain features of depression. Hypothesizes that disturbances in central serotonergic functions form the common root for disturbances in regulation of mood and of aggression. (ABB)

Relations between structure and function of the Golgi apparatus are emerging from recent laboratory work on this cellular organelle which modifies proteins, sorts them, and packages them for delivery. The structure's three specialized compartments are explained through discussions of the glycosylation pathway, density-gradient experiments,…

Presents a hypothesis about the biochemical processes involved in memory storage. The postulated mechanism is initiated by a signal that is unusual but not unlikely to occur and produces an irreversible change in a key component of synaptic chemistry. Other features of the mechanism and experiments supporting the hypothesis are considered. (JN)

Presented are eight abstracts of a symposium held in conjunction with the American Physiological Society (APS) and the American Society of Zoologists (ASZ). Fish gill structure and function, renal function, acid-base balance and ionic sensitivity are topics discussed. (EB)

Presented are issues related to genetic engineering. Increased knowledge of techniques to manipulate genes are apt to create confusion about moral values in relation to unborn babies and other living organisms on earth. Human beings may use this knowledge to disturb the balance maintained by nature. (PS)

Analyzes student responses to an examination question requiring an understanding of the principles of genetic coding and suggests reasons for the misconceptions revealed. (AL)