Laboratory safety ethics education is paramount for the success of modern pharmacy education, cultivating responsible professionals who prioritize safety and ethical conduct. In applied pharmacy programs, laboratories serve as crucial learning environments, but they also present inherent risks. While Environmental, Health, and Safety (EHS) principles offer a robust framework for promoting laboratory safety and ethical conduct, their current integration within pharmacy curricula remains inconsistent and fragmented. This study analyzes the existing gaps in laboratory safety ethics education within applied pharmacy programs. Furthermore, the study investigates the challenges faced by these programs. Based on this analysis, the paper proposes a comprehensive framework for developing a robust safety ethics education system grounded in EHS principles. This framework emphasizes the importance of integrating EHS principles across the curriculum, utilizing innovative teaching methods, fostering a strong safety culture, and leveraging school-enterprise collaborations. By addressing these critical areas, this study aims to contribute to the enhancement of laboratory safety, the cultivation of ethical pharmacists, and the overall quality of applied pharmacy education.