In this article, the authors take a very conservative view of the contribution of animal models to an understanding of human development. We do not think that homologies can be readily documented with even our most closely related relatives' behavior and psychological functioning. The major contribution of animal models is their provision of food…

Evidence about memory for order information comes from a number of different methodologies: human cognition, patient studies, neuroimaging studies, and animal lesion and behavioral studies. The present article discusses (a) evidence that order and item memory are separable; (b) proposed mechanisms for order memory (interitem associations, direct…

Pigeons pecked left versus right keys contingent upon the color presented at 1 of those locations. Spatial-response latencies were shorter when the color appeared at the same location as the required response than at the opposite location. This Simon effect occurred when the stimulus on the alternative key was constant, varied from trial to trial,…

All life begins in the sea, people are taught, and a great transformation extends it to new places on land. The sea has always echoed this transformation in images of human aspiration in myths and metaphors. In the summer of 2003, this powerful image appeared again in the movies. In three very different films, "Seabiscuit," "Whale Rider," and…

For 25 years now, there has been a serious attempt to get at the fundamental cause(s) of dyslexia in our laboratory. A great deal of research has been carried out on the psychological and brain underpinnings of the linguistic dysfunctions seen in dyslexia, but attempts to get at its cause have been limited. Initially, observations were made on the…

Adults often express concern about the increasing production of books with scatological humour despite the evidence of the popularity of such literature with children. This article explores a range of recently published picture books where the anthropomorphic dog is subject to children's laughter. Bakhtin's theory of the carnivalesque is…

Drug ototoxicity research has relied traditionally on animal models for the discovery and development of therapeutic interventions. More than 50 years of research, however, has delivered few--if any--successful clinical strategies for preventing or ameliorating the ototoxic effects of common pharmacological drugs such as aminoglycoside…

Cholinergic systems are critical to the neural mechanisms mediating learning. Reduced nicotinic cholinergic receptor (nAChR) binding is a hallmark of normal aging. These reductions are markedly more severe in some dementias, such as Alzheimer's disease. Pharmacological central nervous system therapies are a means to ameliorate the cognitive…

The cGMP-dependent protein kinase (PKG) has many cellular functions in vertebrates and insects that affect complex behaviors such as locomotion and foraging. The "foraging" ("for") gene encodes a PKG in "Drosophila melanogaster." Here, we demonstrate a function for the "for" gene in sensory responsiveness and nonassociative learning. Larvae of the…

To investigate whether motor skill learning depends on de novo protein synthesis, adult rats were trained in an acrobatic locomotor task (accelerating rotarod) for 7 d. Animals were systemically injected with cycloheximide (CHX, 0.5 mg/kg, i.p.) 1 h before sessions 1 and 2 or sessions 2 and 3. Control rats received vehicle injections before…

Just a little over a century has passed since Muller and Pilzecker (1900) proposed the "perseveration-consolidation" hypothesis suggesting that neural activity initiated by newly learned information perseverates for a while and that such perseveration is critical for consolidating memory. Although memory consolidation is currently the focus of…

There is a close correlation between long-term potentiation (LTP) in the synapses of lateral amygdala (LA) and fear conditioning in animals. We predict that reversal of LTP (depotentiation) in this area of the brain may ameliorate conditioned fear. Activation of group II metabotropic glutamate receptors (mGluR II) with DCG-IV induces…

Three experiments directly compared infants' categorization in variations of the visual familiarization task. In each experiment, 4- or 6-month-old infants were familiarized with a collection of dogs or cats and then their response to novel dogs and cats was assessed. In Experiment 1, 4-month-old infants responded to the exclusive distinction of…

Photography makes an easy and excellent tool for teaching field biology courses, allowing students to study nature without harming it. This photographic technique is used in capturing images of vertebrates, invertebrates, and plants during class field trips, then making these images available for students to identify and study from a departmental…

Courses in Introductory Biology typically include a laboratory assignment in which students generate a dichotomous key. The exercise is designed to help students gain skills in observation, to recognize character differences, to develop vocabulary to communicate those differences, to understand the basis of either Linnaean of cladistic…