Organic molecules are invisible objects, but they can be visualized and manipulated by using molecular models. The object-based learning (OBL) approach, which is an educational tool developed for museums and collection items, is tailored and applied to a first-year bachelor course of organic chemistry. At the beginning of the course, each student…

In this two-session experiment for an organic chemistry lab, students prepare a macrocyclic host compound--namely, a pillar[5]arene--by means of a templated 1,4-dimethoxybenzene/formaldehyde cyclo-oligomerization (session 1), and then, they explore its molecular recognition properties toward the 1,8-diaminooctane guest with the aid of [superscript…

Most chemistry instruction and assessment lie in the symbolic domain of Johnstone's representational levels, despite years of chemistry education researchers calling for increased emphasis to be placed on the molecular or particulate level of chemistry. Without a deep understanding of the particulate nature of matter and molecular-level…

Periodicity in electronic molar entropy values has been shown on the basis of the electronic structures of the elements. Also, with the approximations discussed herein, one can estimate the electronic molar entropy without atomic spectroscopy results. All of this can be accomplished by showing the connection between the vector model of the atom…

The NMR spectrometer is a commonly used spectroscopic instrument that records resonance frequencies of nuclei present in molecular systems. While the NMR frequencies fall within the radio frequency regime for a given molecular system, they are presented in terms of chemical shifts in the audio frequency regime, thereby having the versatility to be…

The COVID-19 pandemic affected a large range of in-person education activities in Colombia. This created great limitations in academic performance for students with reduced access to communication technologies and deepened the educational gaps in the country. This was particularly true for sciences such as biochemistry. In Colombia, molecular…

Visual representations in molecular biology tend to follow a set of shared conventions for using certain shapes and symbols to convey information about the size and structure of nucleotides, genes, and chromosomes. Understanding how and why biologists use these conventions to represent DNA is a key part of visual literacy in molecular biology.…

Structure-function relationships are a core concept in many STEM disciplines. Most biology curricula introduce students to macromolecules, their building blocks, and other small molecules that play key roles in biological processes. However, the shapes, interactions, and functions of these molecules are often discussed using schematic diagrams,…

Appealing to students' affect in academic settings, such as demonstrating chemistry's relevance to their life, is one strategy instructors may use to support students' in learning. This study investigates the types of connections that students make to organic chemistry when responding to an open-ended writing assignment. Students enrolled in an…

A mixture of salt water and isopropyl alcohol is immiscible, forming two separate liquids with the organic layer on top and aqueous layer on bottom. When universal indicator is added to such a mixture, all of the indicator compounds in the universal indicator preferentially dissolve in the alcohol--except for phenolphthalein at high pH. Mixtures…

Nanoscience and Technology (NST) have revolutionized the world. It has led to many innovations since it entered our lives. Meanwhile, the number and quality of people trained in this field gained importance. Currently, initiatives are being taken to integrate this field into the primary education curriculum in many countries. This study focuses on…

High-resolution mass spectrometry (HRMS) is an analytical technique that is typically used by mass spectrometry experts. However, with recent advancements, it is becoming more accessible to students in organic chemistry laboratories. Still, a significant knowledge gap exists between these experts and students. A straightforward laboratory…

Magnetic molecular models help students explore molecular structures and interactions. In this study, we investigated how pairs of students used magnetic models to explore hydrogen bonding and the 6-fold symmetry of snowflakes. Fourteen first-year students enrolled in a chemistry unit participated in pairs. Students' interactions with the magnetic…

Benzoin, an [alpha]-hydroxy ketone, is stereoselectively reduced by sodium borohydride to yield hydrobenzoin, the stereochemistry of which is determined by acetalization and analysis of the derivative by NMR spectroscopy. This classical experiment has been enhanced by modern spectroscopic and computational analysis to enable students to…

Chemistry students should learn not only the key concepts and processes of the discipline but also how they arise, are established, and develop over time. Undergraduate programs for chemistry teachers seldom include training in the history of chemistry to prepare future teachers to put concepts in a historical context. In schools, atom and atomic…