Background: Treatment for oral or oropharyngeal squamous cell carcinoma (O&OSCC) often leads to problems with speech articulation. Articulatory-kinematic data may be especially informative in designing new therapeutic approaches for individuals treated for these tumours. Aims: To provide a systematic review of the literature assessing the…

Objective: Vaping, initially a smoking cessation aid, is now a widespread recreational activity sometimes associated with perceived health concerns. This study explored attitudes, harm perceptions and cessation barriers in the context of participants' vaping behaviours, guided by the theoretical lens of fundamental social causes. Design and…

Computer Aided Detection (CAD) has been used to help readers find cancers in mammograms. Although these automated systems have been shown to help cancer detection when accurate, the presence of CAD also leads to an over-reliance effect where miss errors and false alarms increase when the CAD system fails. Previous research investigated CAD systems…

In 2002, the Swedish National Food Agency and researchers from Stockholm University made an announcement regarding the presence of acrylamide in carbohydrate-rich foods that are exposed to high temperatures, with cereals, potatoes, and coffee possibly being the most significant sources of ingestion. Although limited data are available on assessing…

Gene therapy has fascinated clinicians, scientists, and patients since decades ago because of its potential to treat a disease at the genetic level. This can be achieved in many ways, including replacing a disease-causing gene with a healthy copy. Gene therapy must overcome complex tissue and cellular barriers to introduce genetic modifications…

Gynecological cancers are among the most prevalent cancers in women, making it essential to enhance women's health and awareness. Education is vital for raising this awareness. Constructivist educational models promote active learning and personal experiences, contrasting with traditional methods that emphasize information transmission. This study…

Background: Traditionally, meta-analysis of time-to-event outcomes reports a single pooled hazard ratio assuming proportional hazards (PH). For health technology assessment evaluations, hazard ratios are frequently extrapolated across a lifetime horizon. However, when treatment effects vary over time, an assumption of PH is not always valid. The…

Black men have a greater risk of prostate cancer as well as worse quality of life and more decisional regret after prostate cancer treatment compared to non-Hispanic White men. Furthermore, patients with prostate cancer who primarily obtain information on the internet have significantly more decisional regret compared to other information sources.…

Adapting interventions to new contexts requires consideration of the needs, norms, and delivery structures of the new setting. We describe how we followed the ORBIT model of intervention development to create Health Insurance Navigation Tools (HINT), a health insurance patient navigation intervention for childhood cancer survivors. By engaging…

Within each of 170 physicians, patients were randomized to access e-assist, an online program that aimed to increase colorectal cancer screening (CRCS), or control. Compliance was partial: 78.34% of the experimental patients accessed e-assist while no controls were provided the access. Of interest are the average causal effect of assignment to…

This study aimed to assess the feasibility of applying two recent phase I meta-analyses methods to protein kinase inhibitors (PKIs) developed in oncology and to identify situations where these methods could be both feasible and useful. This ancillary study used data from a systematic review conducted to identify dose-finding studies for PKIs. PKIs…

The effective implementation of evidence-based teaching (EBT) in large college courses benefits from the successful use of instructional teams. An instructional team's feedback allows instructors to act based on evidence of student learning, addressing students' needs. This feedback may be particularly important for novice instructors or…

Background and objective: The aim of this study is to determine the knowledge, attitudes, and behaviors regarding testicular cancer and testicular self-examination (TSE) among medical faculty students in their last two semesters before beginning clinical practice. This study also investigates their beliefs about the importance and efficacy of…

On March 7, 1962 the Royal College of Physicians published a report entitled "Smoking and Health" that made the causal link between smoking and lung cancer clear and explicit. Using a historical data set that contains information on smoking from 1958 to 1965, I find a decrease in smoking for those with more schooling after the report's…

We follow a radioactive sample from production in a reactor to its use in a biological application to model the complexities in the use of radioactive isotopes from a student's perspective. Specifically, we describe a way to use gamma ray detection outside the body to estimate the clearance rate of these radioisotopes from the body and how that…