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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2008
Mutational inactivation of a specific gene is the most powerful technique to analyze the biological function of the gene. This approach has been used for a long time in viruses, bacteria, yeast, and fruit fly, but looked quite hopeless in more complex organisms. Targeted inactivation of specific genes (also known as knock-out mutation) in mice is…
Descriptors: Genetics, Biology, Problem Solving, Science Instruction
Peppink, D.; Douma-Kloppenburg, D. D.; de Rooij-Askes, E. S. P.; van Zoest, I. M.; Evenhuis, H. M.; Gille, J. J. P.; van Hagen, J. M. – Journal of Intellectual Disability Research, 2008
Background: Determining the aetiology of intellectual disability (ID) enables anticipation of specific comorbidity and can thus be beneficial. Blood sampling, however, is considered stressful for people with ID. Our aim was to evaluate the feasibility of a non-invasive screening technique of nine microdeletions/duplications among adults with ID of…
Descriptors: Mental Retardation, Identification, Genetics, Sampling
Barnett, Kylie J.; Finucane, Ciara; Asher, Julian E.; Bargary, Gary; Corvin, Aiden P.; Newell, Fiona N.; Mitchell, Kevin J. – Cognition, 2008
The term synaesthesia has been applied to a range of different sensory-perceptual and cognitive experiences, yet how these experiences are related to each other is not well understood. Not only are there disparate types of synaesthesia, but even within types there are vast individual differences in the way that stimuli induce synaesthesia and in…
Descriptors: Individual Differences, Cognitive Ability, Sensory Experience, Perceptual Development
Price, Johanna R.; Roberts, Joanne E.; Hennon, Elizabeth A.; Berni, Mary C.; Anderson, Kathleen L.; Sideris, John – Journal of Speech, Language, and Hearing Research, 2008
Purpose: This study compared the syntax of boys who have fragile X syndrome (FXS) with and without autism spectrum disorder (ASD) with that of (a) boys who have Down syndrome (DS) and (b) typically developing (TD) boys. Method: Thirty-five boys with FXS only, 36 boys with FXS with ASD, 31 boys with DS, and 46 TD boys participated. Conversational…
Descriptors: Verbs, Nouns, Syntax, Down Syndrome
Kolata, Stefan; Light, Kenneth; Matzel, Louis D. – Intelligence, 2008
It has been established that both domain-specific (e.g. spatial) as well as domain-general (general intelligence) factors influence human cognition. However, the separation of these processes has rarely been attempted in studies using laboratory animals. Previously, we have found that the performances of outbred mice across a wide range of…
Descriptors: Experiments, Spatial Ability, Genetics, Animals
Dolan, Erin L.; Lally, David J.; Brooks, Eric; Tax, Frans E. – Science Teacher, 2008
In this article, the authors describe a large-scale research collaboration, the Partnership for Research and Education in Plants (PREP), which has capitalized on publicly available databases that contain massive amounts of biological information; stock centers that house and distribute inexpensive organisms with different genotypes; and the…
Descriptors: Investigations, Partnerships in Education, Internet, Educational Resources
Case, Emily – American Biology Teacher, 2008
Taxonomy, the identification, naming, and classification of living things, is an indispensable unit in any biology curriculum and indeed, an integral part of biological science. Taxonomy catalogues life's diversity and is an essential tool for communication. Textbook discussions of taxonomy range anywhere from three to eight domains of kingdoms.…
Descriptors: Textbooks, Biology, Classification, High Schools
Campbell, Dennis J.; Reilly, AmySue; Henley, Joan – Education and Training in Developmental Disabilities, 2008
This paper describes a research study that assessed young children with a low incidence disability, specifically Cri-du-Chat Syndrome (CDSC). A description of the concerns of assessing individuals with low incidence disabilities is described. Parent reports (using the Development Observation Checklist System) on the functioning of their children…
Descriptors: Disabilities, Genetic Disorders, Children, Adolescents
Gelinas, Jennifer N.; Tenorio, Gustavo; Lemon, Neal; Abel, Ted; Nguyen, Peter V. – Learning & Memory, 2008
Activation of Beta-adrenergic receptors (Beta-ARs) enhances hippocampal memory consolidation and long-term potentiation (LTP), a likely mechanism for memory storage. One signaling pathway linked to Beta-AR activation is the cAMP-PKA pathway. PKA is critical for the consolidation of hippocampal long-term memory and for the expression of some forms…
Descriptors: Persistence, Stimulation, Long Term Memory, Cognitive Processes
Phenotypical Characteristics of Idiopathic Infantile Nystagmus with and without Mutations in "FRMD7"
Thomas, Shery; Proudlock, Frank A.; Sarvananthan, Nagini; Roberts, Eryl O.; Awan, Musarat; McLean, Rebecca; Surendran, Mylvaganam; Kumar, A. S. Anil; Farooq, Shegufta J.; Degg, Chris; Gale, Richard P.; Reinecke, Robert D.; Woodruff, Geoffrey; Langmann, Andrea; Lindner, Susanne; Jain, Sunila; Tarpey, Patrick; Raymond, F. Lucy; Gottlob, Irene – Brain, 2008
Idiopathic infantile nystagmus (IIN) consists of involuntary oscillations of the eyes. The familial form is most commonly X-linked. We recently found mutations in a novel gene "FRMD7" (Xq26.2), which provided an opportunity to investigate a genetically defined and homogeneous group of patients with nystagmus. We compared clinical features and eye…
Descriptors: Visual Impairments, Eye Movements, Visual Acuity, Depth Perception
Peer reviewedSkena, K. George – Technology Teacher, 1992
Reviews new developments in biotechnology--designer enzymes, biomining, gene cloning. Includes student outcomes, quiz, glossary, and a design brief on genetics. (SK)
Descriptors: Botany, DNA, Emerging Occupations, Enzymes
Davis, Alison – National Institute of General Medical Sciences (NIGMS), 2009
Do people realize that chemistry plays a key role in helping solve some of the most serious problems facing the world today? Chemists want to find the building blocks of the chemical universe--the molecules that form materials, living cells and whole organisms. Many chemists are medical explorers looking for new ways to maintain and improve…
Descriptors: Chemistry, Public Health, Molecular Structure, Health Services
National Institute of General Medical Sciences (NIGMS), 2009
Computer advances now let researchers quickly search through DNA sequences to find gene variations that could lead to disease, simulate how flu might spread through one's school, and design three-dimensional animations of molecules that rival any video game. By teaming computers and biology, scientists can answer new and old questions that could…
Descriptors: Science Careers, Computers, Genetics, Biology
Schneider, A.; Hagerman, R. J.; Hessl, D. – Developmental Disabilities Research Reviews, 2009
Fragile X syndrome (FXS), a single gene disorder with an expanded CGG allele on the X chromosome, is the most common form of inherited cognitive impairment. The cognitive deficit ranges from mild learning disabilities to severe intellectual disability. The phenotype includes hyperactivity, short attention span, emotional problems including…
Descriptors: Genetic Disorders, Mental Retardation, Learning Disabilities, Attention Deficit Hyperactivity Disorder
Dewaele, Jean-Marc; van Oudenhoven, Jan Pieter – International Journal of Multilingualism, 2009
The present study investigates the link between multilingualism/multiculturalism, acculturation and the personality profile (as measured by the Multicultural Personality Questionnaire) of 79 young London teenagers, half of whom were born abroad and had settled down in London during their childhood "Third Culture Kids" (TCKs; Pollock…
Descriptors: Personality Measures, Adolescents, Cultural Awareness, Questionnaires

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